Boston-based Brigham and Women's Hospital realized in the initial days of the pandemic that Spanish-speaking Latino COVID-19 patients were faring worse than those who spoke English, reports NPR. 

Early data suggests the COVID-19 vaccine does not pose serious safety risks for pregnant women, CDC researchers said in a study published April 21 in The New England Journal of Medicine.

Maine may be facing two concurrent COVID-19 epidemics — known as a "syndemic" — among older adults and young people that are driving up cases in the state, Maine's top health official told local CBS affiliate WABI April 21.

New Hampshire has the highest percentage of its population who've received at least one COVID-19 vaccine, according to the CDC's COVID-19 vaccine distribution and administration data tracker.

Maine has the highest percentage of its population fully vaccinated against COVID-19, according to the CDC's COVID-19 vaccine distribution and administration data tracker.

New Hampshire has administered the highest percentage of COVID-19 vaccines they have received, according to the CDC's COVID-19 vaccine distribution and administration data tracker.

As of April 22, more than 568,000 people in the U.S. have died after contracting COVID-19, according to The New York Times.

Based on antibody testing, health officials estimate about 1 in 4 adults in New York City contracted COVID-19 during the city's first surge last spring, according to a study published in The Journal of Infectious Diseases.

About 75 percent of all new COVID-19 cases reported in the U.S. last week were in Michigan, Florida, New York, Pennsylvania and New Jersey, reports The Wall Street Journal.

North Dakota has the most confirmed COVID-19 cases per 100,000 population of all U.S. states, while Hawaii has the fewest, according to an analysis by The New York Times.

Older adults are currently the most vaccinated age group in the U.S., though about a fifth of those 65 and older haven't received even one shot, reports the CDC.

The U.S. State Department plans to significantly increase the number of countries it is warning Americans not to travel to as COVID-19 cases rise globally, reports The Washington Post.

Most Americans agree with the CDC and FDA's pause on Johnson & Johnson's one-dose COVID-19 vaccine as the agencies review cases of rare but serious blood clots in people who've received the shot, according to an Axios/Ipsos poll published April 20.  

Researchers at Texas A&M University in College Station have identified a new coronavirus variant, according to an April 19 news release.

Colorado is on the verge of a fourth COVID-19 surge as cases and hospitalizations rise, officials said. At the same time, the state has relaxed some of its pandemic safety regulations, The New York Times reported April 18. 

The nation has watched as COVID-19 cases, hospitalizations and deaths surge in Michigan, which experts believe may be due, in part, to a high level of variant spread. 

The seven-day average number of COVID-19 vaccines administered daily was 3.3 million as of April 15, a 10.3 percent increase from the previous week's average, according to the CDC's COVID Data Tracker Weekly Review published April 16. 

Early research estimates have shown anywhere between 10 percent to 30 percent of people with COVID-19 go on to become long-haulers, or those who experience persistent symptoms weeks or months after the infection has cleared. With more than 31.2 million COVID-19 cases reported in the U.S., and with the pandemic still raging, the number of people who are or will experience long-term effects presents health systems a profound challenge. 

All states reported minimal flu activity for the 11th consecutive week, excluding Washington, D.C., which reported insufficient data, according to the CDC's FluView report for the week ending April 10.

The CDC is urging public health powers to improve HIV prevention and treatment for transgender women, according to a National HIV Behavioral Surveillance report published in April.