The 10 diseases that caused 75% of US deaths in 2021

Heart disease, cancer and COVID-19 were responsible for nearly half of U.S. deaths in 2021, according to a report by USA Facts, a nonprofit organization that conducts data analysis.

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The report, published Oct. 6, analyzed CDC data to determine the most common diseases in the U.S. in 2021. These 10 diseases accounted for 74.5% of deaths that year.

Here are the 10 diseases that caused the most deaths that year:

  1. Heart disease — 695,547
  2. Cancer — 605,213
  3. COVID-19 — 416,893
  4. Unintentional injuries (accidents) — 224,935
  5. Stroke — 162,890
  6. Chronic lower respiratory disease — 142,342
  7. Alzheimer’s disease — 119,399
  8. Diabetes — 103,294
  9. Chronic liver disease and cirrhosis — 56,585
  10. Kidney disease — 54,358
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