Researchers conducted a systematic review and reanalysis of studies gathered from six major databases and conference abstracts. They used effective practice and organization of care quality criteria to analyze the studies. They identified 76 studies assessing interventions for carbapenem-resistant Enterobacteriaceae (CRE), carbapenem-resistant Acinetobacter baumannii (CRAB) and carbapenem-resistant Pseudomonas aeruginosa (CRPsA).
The study shows interventions were implemented using a multimodal approach in
• 10 of 11 CRE-focused studies
• Four of five CRAB-focused studies
• Three of three CRPsA-focused studies
The most frequent intervention components included:
• Contact precautions: 90 percent
• Active surveillance cultures: 80 percent
• Monitoring, audit and feedback of measures: 80 percent
• Patient isolation or cohorting: 70 percent
• Hand hygiene: 50 percent
• Environmental cleaning: 40 percent
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