Fortune 500's top 25 healthcare companies

The 69th Fortune 500 was released June 5. The annual list of the largest corporations in the U.S. ranked by revenue for the 2022 fiscal year.

Key healthcare takeaways from the most recent listing from Fortune: 

1. The list includes 12 companies specializing in medical facilities. Of those, Nashville, Tenn.-based HCA Healthcare reigns, holding the 66th spot overall with $60.23 billion in revenue, up 2.5 percent year over year. 

2. The list includes eight health insurance and managed care companies. UnitedHealth Group comes out on top in this group, landing fifth in the Fortune 500 rankings overall with $324.16 billion in revenue, up 12.7 percent year over year. 

3. Fourteen pharmaceutical and health service companies are ranked, with CVS Health in the top spot of this group. It holds the sixth spot in the Fortune 500 rankings overall with $322.46 billion in revenue, up 10.4 percent year over year. 

4. Walmart holds the No. 1 spot in the Fortune 500 rankings overall, with revenue of $611.28 billion, up 6.7 percent year over year. Amazon holds the No. 2 spot with $513.98 billion in revenue, up 9.4 percent year over year; Exxon Mobil holds down No. 3 with $413.68 billion in revenue, up a significant 44.8 percent year over year. 

Here are the top 25 ranked healthcare companies with their revenue and percent change to annual revenue: 

1. UnitedHealth Group (No. 5 on Fortune 500)
2022 revenue: $324.16 billion 
Change to revenue: 12.7 percent

2. CVS Health (No. 6 on Fortune 500)  
2022 revenue: $322.46 billion 
Change to revenue: 10.4 percent

3. McKesson (No. 9 on Fortune 500)  
2022 revenue: $263.96 billion 
Change to revenue: 10.8 percent

4. AmerisourceBergen (No. 11 on Fortune 500)  
2022 revenue: $238.58 billion 
Change to revenue: 11.5 percent

5. Cardinal Health (No. 14 on Fortune 500)  
2022 revenue: $181.36 billion 
Change to revenue: 11.6 percent

6. Cigna (No. 15 on Fortune 500)  
2022 revenue: $180.51 billion 
Change to revenue: 3.7 percent

7. Elevance Health (No. 22 on Fortune 500)  
2022 revenue: $156.59 billion 
Change to revenue: 13 percent

8. Centene (No. 25 on Fortune 500)  
2022 revenue: $144.54 billion 
Change to revenue: 14.7 percent

9. Pfizer (No. 38 on Fortune 500)  
2022 revenue: $100.33 billion 
Change to revenue: 23.4 percent

10. Johnson & Johnson (No. 40 on Fortune 500)  
2022 revenue: $94.94 billion 
Change to revenue: 1.2 percent

11. Humana (No. 42 on Fortune 500) 
2022 revenue: $92.87 billion 
Change to revenue: 11.8 percent

12. HCA Healthcare (No. 66 on Fortune 500) 
2022 revenue: $60.23 billion 
Change to revenue: 2.5 percent

13. Merck (No. 69 on Fortune 500) 
2022 revenue: $59.28 billion 
Change to revenue: 15.8 percent

14. Abbvie (No. 73 on Fortune 500) 
2022 revenue: $58.05 billion 
Change to revenue: 3.3 percent

15. Bristol-Myers Squibb (No. 95 on Fortune 500) 
2022 revenue: $46.15 billion 
Change to revenue: -0.5 percent

16. Abbott Laboratories (No. 99 on Fortune 500) 
2022 revenue: $43.65 billion 
Change to revenue: 1.3 percent

17. Molina Healthcare (No. 126 on Fortune 500) 
2022 revenue: $31.97 billion 
Change to revenue: 15.1 percent

18. Danaher (No. 132 on Fortune 500)  
2022 revenue: $31.47 billion 
Change to revenue: 6.9 percent

19. Eli Lilly (No. 142 on Fortune 500)  
2022 revenue: $28.54 billion 
Change to revenue: 0.8 percent

20. Gilead Sciences (No. 150 on Fortune 500)  
2022 revenue: $27.28 billion 
Change to revenue: -0.1 percent

21. Amgen (No. 154 on Fortune 500)  
2022 revenue: $26.32 billion 
Change to revenue: 1.3 percent

22. Becton Dickinson (No. 209 on Fortune 500)  
2022 revenue: $19.40 billion 
Change to revenue: -4.1 percent

23. Moderna (No. 211 on Fortune 500)  
2022 revenue: $19.26 billion 
Change to revenue: 4.3 percent

24. Tenet Healthcare (No. 215 on Fortune 500)  
2022 revenue: $19.17 billion 
Change to revenue: -1.6 percent

25. Stryker (No. 224 on Fortune 500)  
2022 revenue: $18.44 billion 
Change to revenue: 7.8 percent

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