Rush University: Subtle Differences in Brain May Indicate Alzheimer's Risk

Subtle differences in brain anatomy among older individuals with normal cognitive skills may be able to predict the risk of developing Alzheimer's disease over the next decade and how quickly symptoms of dementia would develop, according to a Rush University Medical Center news release.

In their analysis of magnetic resonance images from two separate study groups, researchers from Rush University Medical Center and Massachusetts General Hospital found that individuals with the thinnest cortical areas had a three-fold greater risk of developing Alzheimer's than those with above-average thickness.

Among those in whom these signature brain areas were the thinnest, 55 percent developed dementia during the study period, compared with 20 percent of those with average cortical thickness and none of those in whom cortical thickness was above average.

Read the news release about brain anatomy and Alzheimer's risk.

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