Study shows antibiotic use accelerates Type 1 diabetes

The long-term use and overuse of antibiotics not only contributes to drug resistance, it can also lead to the onset of Type 1 diabetes, according to new research from the University of British Columbia in Vancouver, Canada.

The authors of the study examined diabetes-onset mice and found the mice susceptible to diabetes were more likely to have more harmful and less beneficial bacteria than those resistant to the disease. Additionally, the research findings showed the harmful bacteria prompted an immune response, which destroyed insulin-producing cells.

"We were able to establish a clear relationship between bacteria, the body's immune reaction and the development of Type 1 diabetes," said senior author and microbiologist Deanna Gibson, PhD. "This is likely to have significant implications for treatment of the disease. The next steps are to narrow in and identify which bacteria induce or perhaps protect against Type 1 diabetes."

Ultimately, if researchers can identify the harmful bacteria, it's more likely they will be able to produce antibiotics more specific than those currently in existence.



More articles on antibiotics:
How 7 hospitals approach antibiotic stewardship
Study finds 'inappropriate' variation in antibiotic prophylaxis for pediatric patients
IDSA, SHEA release new antibiotic stewardship guidelines: 4 things to know

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