Researchers divided the hospitals into three groups. They implemented antibiotic stewardship programs of escalating intensity at each group of hospitals.
• Group 1 received basic antibiotic stewardship education and tools as well as access to an infectious disease hotline and antibiotic utilization data
• Group 2 hospitals received those interventions in addition to advanced education, audit and feedback for select antibiotics and locally controlled antibiotic restrictions
• Group 3 hospitals received all the interventions for group 2 as well as audit and feedback on the majority of antibiotics; additionally, an infectious diseases-trained clinician approved restricted antibiotics and reviewed microbiology results
The study shows hospitals in group 3 experienced reductions in total and broad-spectrum antibiotic use during the intervention period as compared to the baseline period. Hospitals in groups 1 and 2 did not experience a reduction in antibiotic use.
“Only the most intensive ASP intervention was associated with reduction in total and broad-spectrum antibiotic use when compared with baseline,” study authors wrote.
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