Two drugs that aren't meant to be taken together can cause negative and sometimes fatal reactions, such as canceling out each others' effects or affecting the body's absorption, excretion and metabolism.
Naveed Saleh, MD, compiled a list of the five deadliest drug interactions for MDLinx. They are:
- Warfarin and antimicrobials
- Warfarin and nonsteroidal anti-inflammatory drugs
- Amiodarone and statins
- Calcium-channel blockers and statins
- PDE-5 inhibitors and nitrates