OpenEvidence, the AI-powered clinical reference app, has become one of the fastest-growing tools in American medicine, fielding 30 million questions last month alone, The New York Times reported June 8.
Here are six things to know about OpenEvidence, according to the story and previous Becker’s reporting:
1. More than half of U.S. physicians are regular users. A 2025 survey found that nearly three times as many physicians use it as ChatGPT, per career platform Offcall.
2. A third of New York City-based Mount Sinai Health System’s 9,000 physicians were already regular users before leadership formally engaged the startup.
3. The company reached a $12 billion valuation in January — up from $3.5 billion the previous July — after raising $250 million in a series D funding round.
4. The app is free to any government-verified physician. Ads — many from drug companies — appear on roughly 5% of queries during the few seconds it takes the AI to respond.
5. OpenEvidence trains its models exclusively on peer-reviewed medical literature, including content licensed from the New England Journal of Medicine and AMA, rather than open-internet data. Rochester, Minn.-based Mayo Clinic researchers have found its answers generally accurate and evidence-based.
6. Mount Sinai embedded a link to OpenEvidence directly within its Epic EHR in March. Sacramento, Calif.-based Sutter Health and Los Angeles-based Cedars-Sinai have also integrated the tool into their clinical workflows.
Becker’s 3rd Annual Fall Chief Pharmacy Officer Summit is the top tier event that the people leading the future of pharmacy convene. This 3-day event is built specifically for Chief Pharmacy Officers and senior pharmacy leaders. The sessions examine the workforce, financial and clinical priorities shaping pharmacy today. Becker’s is where candid discussions flourish and new ideas thrive. Becker's 3rd Annual Fall Chief Pharmacy Officer Summit
