2025 marked the return of the “unicorn” in healthcare.
Sixteen U.S.-based health tech startups surpassed $1 billion in valuation last year, more than double the number in 2024. It reflected the continued concentration of venture capital funding in digital health, largely focused on AI-powered companies.
Here are the healthcare-specific startups that became unicorns in 2025 (in alphabetical order, along with their specialties):
— Abridge: AI scribes
— Ambience Healthcare: AI scribes
— Chapter: Medicare guidance
— Curative: Payer
— Enveda: AI-powered drug discovery
— Function: Lab testing
— Hippocratic AI: Healthcare large language models
— Judi Health: Medical claims administration
— NewLimit: Longevity-focused biotech
— Nourish: Dietary telehealth
— OpenEvidence: Clinical decision support
— Pathos: AI-powered drug development
— Strive Health: Value-based kidney care
— Tala Health: Agentic AI
— Thyme Care: Oncology navigation
— Truveta: EHR data analytics
At the Becker's 11th Annual IT + Revenue Cycle Conference: The Future of AI & Digital Health, taking place September 14–17 in Chicago, healthcare executives and digital leaders from across the country will come together to explore how AI, interoperability, cybersecurity, and revenue cycle innovation are transforming care delivery, strengthening financial performance, and driving the next era of digital health. Apply for complimentary registration now.