Pelvic inflammatory disease not a strong risk factor for ovarian cancer

Pelvic inflammatory disease has been proposed as a risk factor for ovarian cancer, however, new evidence shows that it is not a strong risk factor, according to a study in Cancer Epidemiology, Biomarkers & Prevention.

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Danish researchers conducted a population-based cohort study, between 1978 and 2012, including 1.32 million women. Among women in the cohort, 81,281 women were diagnosed with pelvic inflammatory disease and 5,356 women developed ovarian cancer during follow-up.

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Overall, researchers found no association between pelvic inflammatory disease and ovarian cancer. However, in histotype-specific analyses, researchers found that women with pelvic inflammatory disease showed an increased risk of developing serous ovarian cancer, the most common type of ovarian cancer. Pelvic inflammatory disease was not convincingly associated with risk of any of the other types of ovarian cancer.

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