For the study, researchers analyzed data obtained during the National Institutes of Health-backed Effects of Aspirin in Gestation and Reproduction study published in 2014. The study enrolled more than 1,000 women who’d previously lost one or two pregnancies and were actively trying to conceive. Women in the study either received a low dose of aspirin every day or a placebo.
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Study participants were assessed for levels of C-reactive protein — which is associated with inflammation — in their blood. The analysis found no significant difference in birth rates among women determined to have low- to mid-levels of CRP. Women presenting high levels of the protein in the placebo group experienced a live-birth rate of 44 percent. Women with high levels of CRP who were given daily low doses of aspirin experienced a live-birth rate of 59 percent.
The study’s authors said more research is needed to confirm the findings and generate further understanding on inflammation’s influence on pregnancy.
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