The study, which has not been peer-reviewed, examined data for patients with COVID-19 from Germany, South Korea, China, Switzerland, Iran, the U.K., U.S., France, Spain and Italy.
Researchers examined the link between vitamin D levels and C-reactive protein concentration in 9,212 healthy participants from the 2009-2010 National Health and Nutrition Examination Survey. They also studied reports of 793 COVID-19 patients.
Researchers found a strong association between low vitamin D levels and high C-reactive protein concentration, which is a marker of cytokine storm, a hyperinflammatory condition that is seen in patients with severe cases of COVID-19. They also found an association between vitamin D deficiency and death.
Researchers estimated that the “risk of severe COVID-19 cases among patients with severe vitamin D deficiency is 17.3 percent, while the risk of severity for patients with normal vitamin D levels is 14.6 percent.”
But this does not mean that people need to start hoarding vitamin D supplements, the researchers said.
“We don’t need to push vitamin D on everybody,” said Vadim Backman, PhD,a professor of biomedical engineering at Evanston, Ill.-based Northwestern University and the study’s leader. “This needs further study, and I hope our work will stimulate interest in this area.”
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