This year at the American Society for Clinical Oncology Annual Meeting in Chicago (ASCO), Memorial Sloan Kettering Cancer Center (MSK) and Quest Diagnostics announced the launch of OncoKB, a publicly accessible, web-based Precision Oncology Knowledge Base that puts information about the oncogenic effects and treatment implications of thousands of unique variants in hundreds of cancer-associated genes at the fingertips of researchers around the world. OncoKB was developed in the Marie Josée & Henry R. Kravis Center for Molecular Oncology (CMO) at MSK.
OncoKB includes annotation for more than 3,000 unique variants in 418 cancer-associated genes, including descriptions of the effects of specific mutations as well as therapeutic implications. Unique to OncoKB is its integration of MSK-internal recommendations, which are provided by the Clinical Genomics Annotation Committee (CGAC), a panel of MSK attending clinicians who are recognized as disease and gene experts in their field. CGAC members advise the OncoKB Team in developing and maintaining content for OncoKB. Click here to continue>
