Health systems across the country have been committing to enterprise-scale AI partnerships throughout 2026, moving beyond isolated pilots toward systemwide deployments spanning clinical documentation, decision support, virtual care and workforce management.
Below are notable enterprise AI deals announced so far this year, according to Becker’s reporting and other sources:
January
- Austin-based University of Texas System and Qualified Health launched a generative AI deployment across all eight UT health institutions. The deal includes a HIPAA-compliant AI chat platform for clinicians, purpose-built agents to close care gaps and clinical quality registries. An earlier pilot at UT Medical Branch generated more than $15 million in run-rate impact within six months.
February
- Philadelphia-based Jefferson Health deepened its AI capabilities through a collaboration with Qualified Health to deploy generative AI across its multi-state network. The enterprise agreement covers clinician productivity tools, AI agents and care gap identification at scale.
March
- The U.S. Department of Veterans Affairs awarded Rise8 and Thoughtworks a contract to scale its ambient AI scribe tool from a 10-site pilot to all 130-plus VA medical centers nationwide. The tool listens to clinician-patient conversations and generates draft clinical documentation, with early pilot results showing strong satisfaction among both clinicians and veterans.
- Camden, N.J.-based Cooper University Health Care selected hellocare.ai as its enterprise platform for AI-assisted intelligent hospital rooms, virtual nursing and virtual patient safety monitoring. The deployment includes fall prevention, real-time fall detection and pressure injury prevention across the health system’s inpatient facilities.
- Tacoma, Wash.-based MultiCare Health System selected hellocare.ai as its enterprisewide platform for virtual care delivery. The platform covers AI-assisted virtual nursing, ambient documentation, hospital at home, remote patient monitoring and digital clinic services.
- Scottsdale, Ariz.-based HonorHealth launched an enterprisewide rollout of Abridge’s ambient AI documentation platform directly to approximately 3,000 physicians and advanced practice providers — bypassing a pilot phase entirely. The wave-based deployment began in February with 500 licenses and scaled systemwide.
- Chesterfield, Mo.-based Mercy signed on with Qualified Health for an enterprise AI platform deployment covering care gap identification, clinician productivity tools and AI-powered workflow automation across its hospital network.
- Atlanta-based Emory Healthcare partnered with Qualified Health for an enterprise deployment of its AI platform, including clinical quality registries and generative AI tools for clinicians.
- Rochester, N.Y.-based University of Rochester Medicine signed with Qualified Health to deploy its enterprise AI platform across clinician workflows. The health system spans eight hospitals and $6 billion in annual revenue.
- New York City-based Mount Sinai Health System inked the first enterprise AI deal with OpenEvidence, integrating the AI clinical decision support platform directly into Epic EHR across all seven hospitals. The deployment extends access to physicians, nurses and pharmacists, who can ask natural-language medical questions and receive answers grounded in peer-reviewed literature within their existing workflow.
April
- Nashville, Tenn.-based Ardent Health completed its enterprise launch of Ambience Healthcare’s ambient AI platform across its ambulatory network’s medical groups. The rollout followed a high-performing pilot across 17 specialties that delivered a 45% decrease in documentation time, a 90% clinician utilization rate and five hours saved per clinician per week.
- Minneapolis-based Allina Health selected hellocare.ai as its enterprise platform for AI-assisted intelligent hospital rooms and virtual care delivery. The deployment includes virtual nursing, virtual sitting, digital whiteboards and patient engagement tools across Allina’s inpatient facilities.
May
- Los Angeles-based Cedars-Sinai deployed OpenEvidence’s enterprise AI clinical decision support platform, integrated directly into Epic EHR. The deal introduces what the companies describe as “patient-aware” clinical AI — clinicians query medical literature contextualized to a specific patient’s record, including comorbidities, medications, allergies and prior procedures.
- Rochester, Minn.-based Mayo Clinic and Bayesian Health announced they had codeveloped an enterprise AI solution to identify hospitalized patients who may benefit from palliative care earlier in their stay. The solution surfaces eligible patients in real time across the health system.
- Charlotte, N.C.-based Advocate Health partnered with AI startup Lind to deploy its clinical trial matching platform across the health system’s cancer care network. The platform embeds into the EHR to automatically screen patients for trial eligibility, reducing assessment time from up to an hour to minutes. A retrospective study found the AI achieved more than 94% agreement with clinical reviewers.
Editor’s note: This is not an exhaustive list. If your health system signed an enterprise AI deal in 2026 and isn’t included, please reach out to gbruce@beckershealthcare.com.
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