Dr. Megerian leads University Hospitals, a $7 billion academic health system with more than 32,000 employees, 21 hospitals and more than 200 physician offices across 16 counties in northeast Ohio. University Hospitals serves as the main teaching hospital for the Case Western Reserve University School of Medicine. He has positioned the system as a national model for the deployment of AI in care delivery, including AI-powered ambient documentation, predictive analytics that enable earlier intervention for conditions such as sepsis, and a partnership with Hippocratic AI to scale voice-based patient engagement. Dr. Megerian also expanded UH’s partnership with Northeast Ohio Medical University to create the Center for Artificial Intelligence & Digital Experience, which develops human-centered AI solutions across care settings. Under his watch, the Harrington Discovery Institute at University Hospitals achieved the first positive phase 3 clinical trial for a Harrington-developed heart attack therapy and identified the first drug shown to reverse Alzheimer’s disease in a mouse model. He has also led a cultural shift toward a “hospitality” mindset that helped UH become one of Forbes‘ top 25 “Dream Employers,” with engagement climbing to 84% and turnover declining to 16% overall. Beyond his executive role, Dr. Megerian continues to see patients, teach and write medical textbooks, including a second edition of Surgery of the Cerebellopontine Angle, and has published more than 130 peer-reviewed manuscripts.
