An analysis of approximately 1.75 million surgical procedures at 314 U.S. hospitals participating in ACS’ National Surgical Quality Improvement Project found the higher the severity of a sepsis infection, the higher the risk of a patient experiencing thrombosis following surgery. The results were presented by Jacques Donze, MD, a research associate in the department of medicine at Brigham and Women’s Hospital in Boston, at the American College of Cardiology annual meeting.
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Forty-eight hours prior to surgery, 7.8 percent of patients had either systemic inflammatory response syndrome — an early form of sepsis — sepsis or septic shock. These patients had a 4.2 percent postoperative thrombosis rate, compared to 1.2 percent rate for patients without sepsis.
Broken down by severity of sepsis, SIRS patients’ risk of thrombosis increased 2.5-fold. Sepsis patients’ risk of thrombosis increased approximately 3.3-fold, and septic shock patients’ risk of thrombosis increased nearly 6-fold.
Dr. Donze suggests the risk-benefit assessment of surgical procedures should consider the presence of sepsis, according to the report.
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