Researchers believe the combination of age, specific anesthetics agents and the number of doses may bring memory impairments and brain inflammation. Sevoflurane, specifically, had a direct effect on neuroinflammation. However, desflurane had no direct effects.
The study observed 6-day-old mice, and conducted memory and learning assessments 24 days later. Mice that had received three doses did significantly less well than a control group at learning the location of a platform and remembering where it had been once removed.
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