A study published in the Journal of Hospital Infection examined the effects of delayed central venous catheter removal on outcomes in patients with Gram-negative catheter-related bloodstream infections.
Researchers retrospectively studied 112 patients with Gram-negative bacteraemia and central venous catheter placement at two tertiary care hospitals between January 2007 and December 2016. They defined delayed central venous catheter removal as removal more than three days after onset of bacteraemia or lack of catheter removal entirely.
Of the 112 patients, 78 had catheter-related bloodstream infections and 34 had Gram-negative bacteraemia from another source. Researchers found delayed central venous catheter removal was associated with increased 30-day mortality in patients with bloodstream infections as compared to those with Gram-negative bacteraemia from another source.
Delayed catheter removal, multi-drug-resistant Gram-negative bacteraemia and chronic renal failure were all associated with 30-day mortality in patients with bloodstream infections. Early catheter removal had a positive effect on mortality rate among those who had multi-drug-resistant Gram-negative bacteraemia.
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