Despite decades of concern over in-bone prosthesis infections, study suggests risk is low

Patients with above-the-knee amputations have been outfitted with prosthetic legs for more than 500 years. But in recent decades, these prostheses have advanced to become in-bone, where the prosthesis is implanted directly into the femur, which grows over the metal, securing it in place. Although infection concerns for these osseointegrated implants have persisted, new research in the Journal of Bone and Joint Surgery suggests those worries may be unfounded.

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Australian researchers tracked outcomes for more than 80 patients who received implants that adhere to bone and found none of the study participants experienced a serious infection. Twenty-six patients reported complications with orthopedic hardware or bone damage, 29 developed low-grade infections that were successfully treated with minimal measures and 31 patients had no complications whatsoever.

“We can confidently say that this type of prosthesis is a viable choice and the new infection classification system, developed by the Osseointegrated Group of Australia, provides an effective tool for the use in patient selection as well as infection management,” concluded study author Munjed Al Muderis, MD, an orthopedic surgeon at MacquarieHospital in Sydney, Australia, in a statement

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