Top 15 US pharmacies by total prescription revenue

Mergers and acquisitions are reshaping the pharmacy and pharmacy benefit manager industries, and the big players are gaining even more market share.

Below are the 15 largest pharmacies in the U.S. by total prescription-dispensing revenue in 2018. The list, compiled by the Drug Channels Institute, counts revenue from mail order, retail and specialty pharmacy prescriptions when applicable. Most pharmacies do not have all three.

1. CVS Health ($102.8 billion)
2. Walgreens Boots Alliance ($74.4 billion)
3. Cigna/Express Scripts ($46.5 billion)
4. OptumRx ($25.9 billion)
5. Walmart ($20.9 billion)
6. The Kroger Co. ($13.4 billion)
7. Rite Aid Corp. ($11.1 billion)
8. Humana Pharmacy Solutions ($6.3 billion)
9. Albertsons ($5.0 billion)
10. Diplomat Pharmacy ($4.8 billion)
11. Costco Wholesale ($2.6 billion)
12. PharMerica ($2.4 billion)
13. Publix ($2.2 billion)
14. Ahold Delhaize ($2.1 billion)
15. H-E-B ($1.8 billion)

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