Most, least expensive US cities for prescription drugs

New York City patients pay 24 percent more than the national average for prescription medications, making it the most expensive city for prescription drugs, according to a list published Feb. 19 by prescription discount service GoodRx. 

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To compile its list, GoodRx examined the prices of the 500 most common prescriptions in 30 of the country’s most populous cities.

Five most expensive cities for prescription medications:

  1. New York City: 24 percent above the national average price
  2. Los Angeles: 13.7 percent above the national average price
  3. San Francisco: 13.6 percent above the national average price
  4. New Orleans: 12.3 percent above the national average price
  5. Milwaukee: 11.2 percent above the national average price

Five least expensive cities for prescription medications:

  1. Denver: 36.5 percent below the national average price
  2. Salt Lake City: 21.6 percent below the national average price
  3. Houston: 20.7 percent below the national average price
  4. Atlanta: 20 percent below the national average price
  5. Dallas: 15.5 percent below the national average price

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