Here are four more notes:
- The company’s stock recently dropped 9% following a disappointing update on the vaccine business in China, further emphasizing the risks of overdependence on one blockbuster drug.
- Keytruda, which generated $29.5 billion in sales in 2024, has driven much of Merck’s growth, but its upcoming patent cliff is casting a shadow over the company’s future.
- Despite new drug acquisitions and a pipeline of promising assets, including in oncology and immunology, investors are worried about the sustainability of Keytruda’s sales post-patent. Merck’s attempts to diversify and mitigate this risk, including the development of a new under-the-skin version of the drug, have yet to fully reassure the market.
- As the 2028 patent expiration looms, Merck is under increased pressure to demonstrate that its growth can continue without Keytruda’s dominance.
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