FDA OKs Ozempic for diabetic kidney disease

The FDA has approved Ozempic to reduce the risk of kidney disease worsening, kidney failure and cardiovascular-related death in adults with Type 2 diabetes and chronic kidney disease. 

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This new approval expands Ozempic’s use, adding to its previous indications for improving glycemic control in Type 2 diabetes and reducing major cardiovascular events in people with heart disease, according to a Jan. 28 news release from Novo Nordisk. 

The basis of the approval was due to a phase 3 trial that demonstrated the drug significantly reduced the risk of kidney disease progression and cardiovascular death by 24%, compared to a placebo, over three years. 

Ozempic was first approved by the FDA in 2017 for blood sugar control in Type 2 diabetes. It received a cardiovascular indication in 2020 and is now the most broadly indicated GLP-1 receptor agonist for managing diabetes, kidney disease and heart risk.

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