AstraZeneca drug regimen approved for endometrial cancer

The FDA approved AstraZeneca’s monotherapy for endometrial cancer, Imfinzi, after it was found in a study to decrease its risk of progression and death by 58% in patients who were diagnosed with advanced or recurrent endometrial cancer that is mismatch repair deficient.

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The study was published in October in the Journal of Clinical Oncology. It found that overall Imfinzi was well tolerated and safety was consistent with previous trials, according to a June 17 news release from AstraZeneca.

Endometrial cancers that are mismatch repair deficient are often seen in 25% to 30% of patients, according to a study published in the International Journal of Gynecological Cancer

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