Sloan Kettering researchers analyze more than 10k patient genomes

A team of researchers from New York City-based Memorial Sloan Kettering Cancer Center analyzed 10,336 patients with MSK-IMPACT, a diagnostic test developed at the center.

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This cohort represents the first set of metastatic cancer patients whose tumors were submitted for clinical genomic sequencing with MSK-IMPACT. The team — led by pathology researchers Ahmet Zehir, PhD, and Ryma Benayed, PhD — published their research in Nature Medicine on May 8.

The study focuses on how this genetic information guided clinical decisions for the participating patients. The team found 11 percent of patients were able to participate in clinical trials of treatments that targeted the genetic alterations identified through MSK-IMPACT.

The MSK-IMPACT data will be shared with the scientific community through a database called cBioPortal.

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