Researchers examined data from patients with sepsis and septic shock reported to the New York State Department of Health from April 1, 2014, to June 30, 2016. Care providers initiated a sepsis protocol for patients within six hours of their arrival in the emergency department. They completed all items in a three-hour sepsis bundle of care within 12 hours of the patients’ arrival. In all, researchers studied data for 49,331 patients at 149 hospitals.
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Care providers completed the three-hour sepsis bundle within three hours for 82.5 percent of the patients. The median time to completion of the three-hour bundle was 1.30 hours; the median time to the administration of antibiotics was 0.95 hours; and the median time to completion of the administration of IV fluid was 2.56 hours.
Among patients who received the three-hour bundle of care within 12 hours, taking more time to initiate the bundle as well as administer antibiotics was associated with higher in-hospital mortality rates. However, taking more time to administer IV fluids did not impact patient death.
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