Top medication spend for cardiopulmonary drugs

Cardiopulmonary medications made up 5.08% of pharmacy program participants’ drug spend from April 2023 to March 2024, according to Vizient’s “Summer 2024 Pharmacy Market Outlook” report. 

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The report, released July 30, analyzed pharmacy program participants’ purchase data from April 2023 to March 2024 and provides an estimate of pharmaceutical price changes for 2025. 

Vizient’s analysts predicted a 3.70% drug price inflation rate for cardiopulmonary medication in 2025, slightly less than the predicted 3.81% overall drug price inflation rate.

The cardiology medications that saw the biggest share of spending were:

  1. Trikafta (elexacaftor/tezacaftor/ivacaftor): 0.58% 
  2. Xolair (omalizumab): 0.52%
  3. Vyndamax (tafamidis): 0.50%
  4. Nucala (mepolizumab): 0.31%
  5. Creon, Zenpep (lipase/protease/amylase): 0.28%
  6. Entresto (sacubitril/valsartan): 0.26%
  7. Adrenalin (epinephrine): 0.23%
  8. Repatha (evolocumab): 0.20%
  9. Fasenra (benralizumab): 0.20%
  10. Pulmozyme (dornase alfa): 0.18%

The top cardiopulmonary medications with the greatest change in spend were:

  1. Norepinephrine bitartrate in 0.9% sodium chloride: 348% increase
  2. Leqvio (inclisiran sodium): 216% increase
  3. Tezspire (tezepelumab-ekko): 188% increase
  4. Phenylephrine HCI in .09% sodium chloride: 143% increase
  5. Vyndamax (tafamidis): 57% increase
  6. Trikafta (elexacaftor/tezacaftor/ivacaftor): 42% increase 
  7. Repatha (evolocumab): 35% increase
  8. Entresto (sacubitril/valsartan): 26% increase
  9. Xolair (omalizumab): 10% increase

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