AHA researchers analyzed PubMed data to study potential shared risk factors between heart failure, atrial fibrillation and coronary heart disease, and cognitive impairment.
Here are seven things to know:
- Approximately 50% of people with heart failure experience cognitive impairment.
- Atrial fibrillation increases an individual’s risk of cognitive impairment by 39%.
- Individuals with coronary heart disease are at a 27% increased risk of developing dementia.
- Up to 50% of heart attack patients experience loss of brain function.
- Shared risk factors between heart failure and cognitive impairment are:
- Reduced blood flow
- Chronic inflammation
- Neurohormonal activation,
- Obesity
- Sleep-disordered breathing
- Gray matter volume reduction and/or white matter damage
- Genetic variations found in both individuals with heart failure and individuals with neurodegenerative diseases such as Alzheimer’s
- Shared risk factors between atrial fibrillation and cognitive impairment are:
- High blood pressure
- Type 2 diabetes
- Heart failure
- Smoking
- Vascular disease
- Sleep-disordered breathing
- Advanced age
- Stroke
- Small brain bleeds or microhemorrhages
- Reduced cardiac output
- Systemic inflammation and inflammatory biomarkers
- Shared risk factors between coronary heart disease and cognitive impairment are:
- High blood pressure
- Type 2 diabetes
- Small vessel disease in the brain and reduced brain blood flow
- Genetic factors associated with heart disease may contribute to brain shrinkage
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