New Mexico researchers develop cholesterol vaccine

Researchers at Albuquerque-based University of New Mexico School of Medicine have created a new LDL cholesterol vaccine.

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The study, published in NPJ Vaccines, tested the vaccine on mice and monkeys with positive results. The vaccine lowers LDL cholesterol almost as effectively as PCSK9 inhibitors, according to a Dec. 14 system news release. It has been tested over the past decade on monkeys and mice with “promising results,” the release said

“The vaccine is based on a non-infectious virus particle,” lead author Bryce Chackerian, PhD, a professor in the molecular genetics and microbiology department at the university, said in the release. “It is just the shell of a virus, and it turns out that we can use that shell of a virus to develop vaccines against all sorts of different things.” 

The vaccine could be cheaper than $100 per dose.

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