Researchers used the Surveillance, Epidemiology and End Results program, the Breast Cancer Surveillance Consortium and the medical literature to study the cost-effectiveness of mammography frequency for women with different breast density at different ages.
They found that biennial mammography cost less than $50,000 per quality-adjusted life-year gained for women who were aged 40-49 years with category 3 or 4 breast density and who had either a previous breast biopsy or a family history of breast cancer. Annual mammography, however, was not cost-effective for any group, regardless of age or breast density.
The researchers concluded that mammography screening should be personalized based on age, breast density, history of breast biopsy, family history of breast cancer and beliefs about the potential benefit and harms of screening.
Read the Annals of Internal Medicine abstract on mammography cost-effectiveness.
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