U.S. overdose deaths declined in 2025, though at a slower pace than the previous year, according to CDC data released Jan. 14.
The data comes as HHS is reversing more than $2 billion in cuts to federal grants supporting mental health and addiction services.
Here are four things to know:
1. There were 72,836 predicted overdose deaths in the 12-month period ending in August 2025 — the most recent data available — representing a 20.6% decrease from the 91,694 predicted deaths during the same period in 2024.
2. In the 12-month period ending in January 2025, there were 79,896 predicted overdose deaths — a 25.3% drop from 106,903 in the previous year.
3. Vermont, Rhode Island and New York had the largest decreases in predicted drug overdose deaths from August 2024 to August 2025, each exceeding 35%.
4. Arizona, New Mexico and Kansas were the only states with projected increases in drug overdose deaths.
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