Vanderbilt to lead $11.2M effort to improve ICU patient outcomes

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Nashville, Tenn.-based Vanderbilt Health has been given an up to $11.2 million, five-year HHS contract to develop a platform to test and validate new technologies designed to improve ICU patient outcomes.

The federal program is called CIRCLE — the Critical Illness Immunological Reprogramming and Control Point Learning Engine — and is part of HHS’ Advanced Research Projects Agency for Health, according to a Sept. 22 news release from Vanderbilt Health.

Focused on ICU patient care, “CIRCLE will harness advances in diagnostics and AI to speed development of next-generation interventions that identify and respond to harmful immunoinflammatory states before life-threatening complications occur,” the release said. 

Vanderbilt Health will develop a platform for testing and validating those interventions nationwide through its Groundbreaking Organization Leveraging Data Insights: Learning for Optimized Critical Care Knowledge and Systems program, also called Goldilocks.

The current timeline to integrate new technologies into patient testing is 12 to 18 months, which Vanderbilt Health plans to reduce to less than 90 days. 

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