Boston-based Massachusetts General Hospital was the highest-performing U.S. healthcare institution on Nature‘s 2026 Research Leaders ranking.
Nature used research output data from 178 publications between Jan. 1, 2025, and Dec. 31, 2025, to assess organizations’ research quality and institutional performance. Read Nature’s full methodology here.
The top 25 U.S. healthcare institutions for research in 2025 were, according to Nature:
- Massachusetts General Hospital (Boston)
- University of Texas Southwestern Medical Center (Dallas)
- Mayo Clinic (Rochester, Minn.)
- Brigham and Women’s Hospital (Boston)
- Mount Sinai Health System (New York City)
- Stanford Medicine (Palo Alto, Calif.)
- Memorial Sloan Kettering Cancer Center (New York City)
- Columbia University Irving Medical Center (New York City)
- University of Texas MD Anderson Cancer Center (Houston)
- NYU Langone Health (New York City)
- University of Colorado Anschutz Medical Campus (Aurora)
- University of California Los Angeles Health
- Boston Children’s Hospital
- Duke University Health System (Durham, N.C.)
- Vanderbilt University Medical Center (Nashville, Tenn.)
- Michigan Medicine (Ann Arbor)
- St. Jude Children’s Research Hospital (Memphis, Tenn.)
- Dana-Farber Cancer Institute (Boston)
- Fred Hutchinson Cancer Center (Seattle)
- University of Washington Medicine (Seattle)
- Cleveland Clinic
- Children’s Hospital of Philadelphia
- University of Texas Health Science Center at Houston
- Beth Israel Deaconess Medical Center (Boston)
- University of Pennsylvania Health System (Philadelphia)
Read Nature‘s full 2026 Research Leaders ranking of healthcare institutions here.
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