A randomized controlled trial was conducted in which 385 patients at cardiovascular risk were given various general anesthetics. Previous evidence had recommended using volatile anesthetics, but the study showed the choice of anesthetic had no impact on ischemic outcomes after non-cardiac surgery.
Of the total patients, 40.8 percent and 40.3 percent assigned to receive sevoflurane and propofol, respectively, had myocardial ischemia within 48 hours of surgery.
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