SEEK, a London, United Kingdom-based pharmaceutical company, developed the vaccine, called AGS-v. The vaccine is intended to provide broad protection against a range of mosquito-transmitted diseases, as opposed to a specific disease. It is designed to start an immune response to mosquito saliva.
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The clinical trial will enroll up to 60 healthy adults, ages 18 to 50 years. The participants will be randomly assigned to receive one of three vaccine regimens — two injections of the AGS-v vaccine; two injections of AGS-v combined with an adjuvant; or two placebo injections of sterile water.
The study is being conducted at the NIH Clinical Center in Bethesda, Md., and is expected to be completed by summer 2018.
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