Their findings were published in the Journal of the Royal Society Interface.
The team tested every possible combination of a group of six antibiotics, including some combinations of three drugs at once. Two of those combinations of three drugs of different classes were more successful than expected.
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“We have a logical, methodical way to identify three-drug combinations to pursue,” said Pamela Yeh, PhD, the study’s lead author. “We think it’s vital to have this framework for identifying the best possible combinations of antibiotics.”
More research is needed to identify which drug combinations would be most effective on different diseases and different parts of the body. The team is now working to test combinations of four antibiotics.
More articles on antibiotic resistance:
E. coli can develop antibiotic resistance in just days, researchers find
Scientists identify gene that prevents TB strains from becoming drug-resistant, study shows
CDC invests millions in antibiotic resistance efforts — where did the money go?
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