Researchers analyzed data from more than 4,000 C. diff patients, 10.1 percent of whom developed a recurrent CDI.
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Patients with community-onset healthcare associated C. diff, more than two hospitalizations two months prior to diagnosis, new gastric acid suppression, use of fluoroquinolone and other high-risk antibiotics at the beginning of the initial CDI as well as increased age predicted CDI recurrence.
Stays in an intensive care unit were associated with a lower risk of redeveloping a CDI.
Flagging patients at risk for recurring CDI could help improve treatment and prevention strategies, the researchers suggested in their abstract.
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