Fluoxetine proves ineffective at treating AFM patients, study finds

The medication fluoxetine may be linked to poorer long-term health outcomes among pediatric patients with acute flaccid myelitis, according to study published in Neurology.

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For the study, researchers examined data on 56 patients diagnosed with AFM between 2015-16 at 12 centers across the U.S. Researchers assessed the outcomes, adverse events and adverse reactions associated with 30 AFM patients treated with fluoxetine and 26 patients who did not receive fluoxetine.

The patients who received fluoxetine had more severe paralysis than those in the control group. They did not experience any serious adverse events after taking the medication, but ultimately demonstrated poorer long-term outcomes.

Researchers concluded fluoxetine was “not associated with improved neurologic outcomes” in these patients.

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