Researchers combed through MEDLINE and EMBASE databases, abstract lists for key conferences and reference lists of key reviews as well as information on unpublished outbreaks from 2000 to 2015. Ninety-eight outbreaks were eligible. They then conducted a narrative synthesis of the evidence.
Here are four findings:
1. The number of CPE infection or colonization cases involved in outbreaks varied widely, from two to 803.
2. In the majority of outbreaks, multi-component infection control measures were used, commonly including: patient screening, contact precautions, hand-washing interventions and enhanced environmental cleaning/decontamination.
3. Researchers identified seven studies providing the best available evidence on the effectiveness of control measures.
4. These studies showed that CPE outbreaks can be controlled successfully by using a range of existing infection control measures.
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