Children born following IVF, ovulation induction may face higher pediatric cancer risk

Mothers who undergo fertility treatments may give birth to children who are at a heightened risk for developing pediatric tumors and cancers, according to study published in the American Journal of Obstetrics & Gynecology.

Israeli researchers conducted a population-based cohort analysis of 242,187 babies born between 1991 and 2013. Of the babies, 237,863 were conceived spontaneously; 2,603 were conceived after in vitro fertilization, and 1,721 were conceived after ovulation induction treatments. The follow-up period was approximately 10.6 years.

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The study shows that in all, providers diagnosed 1,498 tumors, indicating a variety of cancers such as leukemia, brain and spinal cord tumors, neuroblastomas, Wilms tumors and Hodgkin and non-Hodgkin lymphoma.

The incidence rate for tumors was highest among children either after IVF (1.5/1000), and slightly lower for OI births (1.0/1000). Naturally conceived children had a low tumor incidence rate (.59/1000).

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