Antibiotic therapy may not alter Enterobacteriaceae bacteraemia-associated mortality in ICUs: 4 insights

Appropriate empiric antibiotic therapy did not change the mortality rate associated with Enterobacteriaceae bacteraemia acquired in intensive care units, according to a study in the Journal of Hospital Infection.

Researchers examined patients who stayed for more than two days in two general ICUs in England between 2002 and 2006.

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Here are four insights:

1. Among 3,411 ICU admissions, 195 acquired Enterobacteriaceae bacteraemia.

2. Enterobacteriaceae bacteraemia was associated with an increase in daily risk of ICU death.

3. It was also associated with a reduced daily risk of ICU discharge.

4. Appropriate empiric antibiotic therapy did not significantly change ICU mortality or discharge.

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