The 25 priciest drug classes for hospitals

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The most expensive drug category for nonfederal hospitals in 2024 were antineoplastic targeted agents, according to a study published in the American Journal of Health-System Pharmacy. 

The report, published by the American Society of Health-System Pharmacists, found that U.S. drug spending rose 10.2% in 2024 to $805.9 billion, driven largely by the increasing use of GLP-1 receptor agonists for obesity and diabetes. 

Here are the top 25 therapeutic drug categories ranked by nonfederal hospital expenditure in 2024: 

  1. Antineoplastic targeted agents: $7.3 billion 
  2. Hemostatic modifiers: $2.99 billion 
  3. Immunologic agents: $2.97 billion 
  4. Biologicals: $2.9 billion 
  5. Hospital solutions: $2.48 billion 
  6. Antiviral drugs: $2.37 billion 
  7. Miscellaneous: $1.9 billion 
  8. Antiinfectives, systemic: $1.54 billion 
  9. Diagnostic aids: $1.47 billion 
  10. Blood factors: $1.4 billion 
  11. Antiarthritics: $958.7 million 
  12. Anesthetics: $949.9 million 
  13. Respiratory therapy agents: $949.1 million 
  14. Diabetes therapies: $844.5 million 
  15. Gastrointestinal agents: $732.8 million 
  16. Musculoskeletal agents: $728.1 million 
  17. Hormones: $724.2 million 
  18. Psychotherapeutics: $697.4 million 
  19. Antineoplastic chemotherapies: $649 million 
  20. Neurological disorder drugs: $564.3 million 
  21. Cardiac agents: $509.1 million 
  22. Vascular agents: $476.8 million 
  23. Analgesics: $445.6 million 
  24. Enzymes: $401.2 million 
  25. Contraceptives: $385.3 million 

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