Retail pharmacies are closing, and the pharmacists who worked in them are leaving, too. Rite Aid filed for bankruptcy in 2023 and shuttered about 800 stores while CVS closed 900 locations beginning in 2021, and Walgreens announced plans to close…

HHS has directed six of its agencies to reduce regulatory barriers associated with clinical trial research to accelerate pharmaceutical development in the U.S. The move — detailed in a road map called Operation TrailBlazer — comes as “a growing share…

The FDA approved 13 new immunotherapies in 2025, down from 22 approvals in 2024, according to the Cancer Research Institute “Cancer Immunotherapy Insights & Impact” report published June 1. The Cancer Research Institute tracks and analyzes FDA cancer immunotherapy approvals…

HHS and the FDA have requested updates to prescribing information for testosterone replacement therapy products, including changes related to age-related hypogonadism, prostate cancer risk and benign prostatic hyperplasia. HHS said it plans to remove a limitation of use stating that…

The Trump administration has escalated its push to reshape global pharmaceutical pricing, opening a formal trade investigation into Germany over what it characterizes as persistent underpayment for innovative drugs — the latest move in a broader campaign to reduce the…

Active drug shortages in the U.S. rose for the second consecutive quarter in 2026, reaching 223 in the first quarter, according to the American Society of Health-System Pharmacists — and the FDA’s database continues to reflect new discontinuations weekly. The…

Eli Lilly has begun denying 340B drug discounts to hospitals that have not submitted claims-level data under its reporting requirements, according to a June 18 news release from the American Hospital Association.  “AHA can confirm that Eli Lilly has taken…

The FDA has approved Utebzi (tebipenem pivoxil), an oral antibiotic for the treatment of complicated urinary tract infections, including pyelonephritis, in adults who have limited or no alternative oral treatment options. The approval makes Utebzi the first and only oral…

The Pharmaceutical Care Management Association, a trade group for pharmacy benefit managers, filed lawsuits in June challenging Illinois and Tennessee pharmacy laws.  PCMA raised Employee Retirement Income Security Act-based preemption counts targeting Illinois’ Prescription Drug Affordability Act. The law, signed…

California, New York and Ohio led all states in gross Medicaid prescription drug spending in fiscal year 2024, accounting for more than a quarter of national spend, according to a KFF analysis of federal data. The figures reflect gross spending…