2025 marked the return of the “unicorn” in healthcare.
Sixteen U.S.-based health tech startups surpassed $1 billion in valuation last year, more than double the number in 2024. It reflected the continued concentration of venture capital funding in digital health, largely focused on AI-powered companies.
Here are the healthcare-specific startups that became unicorns in 2025 (in alphabetical order, along with their specialties):
— Abridge: AI scribes
— Ambience Healthcare: AI scribes
— Chapter: Medicare guidance
— Curative: Payer
— Enveda: AI-powered drug discovery
— Function: Lab testing
— Hippocratic AI: Healthcare large language models
— Judi Health: Medical claims administration
— NewLimit: Longevity-focused biotech
— Nourish: Dietary telehealth
— OpenEvidence: Clinical decision support
— Pathos: AI-powered drug development
— Strive Health: Value-based kidney care
— Tala Health: Agentic AI
— Thyme Care: Oncology navigation
— Truveta: EHR data analytics
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