Larry Ellison-funded cancer research center to lay off 88

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Los Angeles-based Ellison Medical Institute, a cancer research center established with funding from Oracle co-founder Larry Ellison, will lay off 88 employees.

The permanent layoffs will take effect Jan. 3, 2027, according to a WARN notice filed Nov. 4 with the California Employment Development Department and reviewed by Becker’s.

The Ellison Medical Institute operates a cancer and preventive medicine clinic, research labs focused on AI and molecular analytics, and a health policy think tank, according to the institute’s website.

The institute was established in 2016 as the Lawrence J. Ellison Institute for Transformative Medicine of USC, backed by a $200 million gift from Mr. Ellison to the University of Southern California in Los Angeles, and later separated from the university, according to a Nov. 12 report from the Los Angeles Times.

Becker’s has reached out to Ellison Medical Institute for comment and will update this story if more information becomes available.

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