Developing skin cancer following transplant surgery is common, study shows

Incidence of skin cancer after organ transplant surgery is common, and significant risk factors include older age, being white and being male, according to a study published in JAMA Dermatology.

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Researchers identified study subjects through the Organ Procurement and Transplantation Network database. They examined 10,649 adult recipients of a primary transplant performed at 26 centers across the United States.

Here are three insights:

1. The overall incidence rates for post-transplant skin cancer was 1,408 per 100,000 person-years.

2. The incidence rates for specific types of skin cancer were as follows:

•    Squamous cell carcinoma: 1,328 per 100 000 person-years
•    Melanoma: 122 per 100 000 person-years
•    Merkel cell carcinoma: 4 per 100 000 person-years

3. Statistically significant risk factors for post-transplant skin cancer included:

•    Pre-transplant skin cancer
•    Male sex
•    White race
•    Age of 50 years or older at transplant surgery
•    Thoracic organ transplantation

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