The inhalant gas anesthetic sevoflurane produced more lactate compared with the intravenous anesthetic propofol, researchers reported. The study explored the potential association between emergence delirium and specific brain metabolites like lactate.
The researchers analyzed 59 children, ages 2 to 7 who underwent magnetic resonance imaging while under anesthesia. The children anesthetized with sevoflurane were associated with higher concentrations of lactate and glucose and emerged from anesthesia with more agitation and dissociate behavior.
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