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Melissa Ortega, PharmD

Chief Pharmacy Officer

Mass General Brigham

Boston, MA

With more than a decade of healthcare leadership, Ms. Ortega oversees the health system’s transformation of pharmacy services across academic medical centers, community hospitals and ambulatory practices. She leads an enterprisewide effort to standardize pharmacy practice, elevate operational efficiency, advance models of care, and embrace a unified system strategy across a pharmacy workforce of more than 1,100 employees with annual drug spending exceeding $1.5 billion. Under her leadership, Mass General Brigham Pharmacy is designing and implementing a systemwide infusion strategy and transformative ambulatory care models that improve medication access and align with population health initiatives. She is also driving a comprehensive sterile compounding licensure strategy to ensure regulatory compliance and harmonizing formularies across the enterprise. Previously she served as system vice president of ambulatory pharmacy services at Boston-based Tufts Medicine and held leadership roles including president and legislative chair of the Massachusetts Society of Health-System Pharmacists and inaugural chair of the American Society of Health-System Pharmacists Section of Community Pharmacy Practitioners. She is actively engaged in national advocacy, research and education.

Becker's Recognition

Melissa Ortega, PharmDhas been named a Becker's honoree on the lists below.

2025 Winner

Executives

Hospital and Health System Chief Pharmacy Officers to Know

Chief pharmacy officers provide systemwide oversight of medication management and drug supply, which in turn creates a safer patient experience. These executives are also responsible for leading cost-effective pharmacy strategy, implementing impactful pharmacy policies, driving automation and technology initiatives, and educating the next generation of pharmacy leaders.

2026 Winner

Executives

101 Hospital and Health System Chief Pharmacy Officers to Know

Chief pharmacy officers provide systemwide oversight of medication management and drug supply, which in turn creates a safer patient experience. These executives are also responsible for leading cost-effective pharmacy strategy, implementing impactful pharmacy policies, driving automation and technology initiatives, and educating the next generation of pharmacy leaders.

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