UCI Health is the only academic health system in Orange County, serving Orange and parts of Los Angeles counties with advanced, research-driven care for a diverse population. The system has expanded significantly with the creation of the UCI Health Community Network in 2024, following the acquisition of four community hospitals and their affiliated physicians and outpatient sites. UCI Medical Center, the flagship hospital, is nationally recognized as one of the nation’s top 10 academic medical centers for quality by Vizient and holds a CMS 4-star patient experience rating. It is home to Orange County’s only National Cancer Institute-designated comprehensive cancer center, the county’s only level 1 trauma center, and numerous regional “onlys,” including a burn center, a high-risk perinatal program and an adult hematopoietic stem cell transplant program. UCI Health leads more than 400 clinical trials, more than any other in the region, giving patients early access to innovative therapies supported by UC Irvine’s world-class research enterprise. In 2024, UCI Health opened the Joe C. Wen & Family Center for Advanced Care and the Chao Family Comprehensive Cancer Center in Irvine, and just opened a first-of-its-kind, all-electric acute care hospital in December 2025, setting a national benchmark for sustainability in healthcare. UCI Health boasts nationally adopted infection-prevention innovations, expanding in-home and telehealth services, and consistent safety and quality recognition.
